Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | SELL | P14151 | 1/20 | 0.42 |
| ▸ | SELP | P16109 | 1/20 | 0.42 |
| ▸ | SELE | P16581 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL201609 | 0.87 | GABRA1 (0.57) | ALDH1A1ALOX15TDP1GABRA1GABRB2 | |
| SCHEMBL3872595 | 0.87 | GABRA1 (0.57) | ALDH1A1ALOX15TDP1GABRA1GABRB2 | |
| Ether SCHEMBL29201870 | 0.86 | ESR1 (0.46) | ALDH1A1ALOX15TDP1GABRA1GABRB2 | |
| Propionic Acid SCHEMBL28907475 | 0.84 | ESR1 (0.45) | ALDH1A1ALOX15TDP1GABRA1GABRB2 | |
| Methane SCHEMBL27627234 | 0.84 | GABRA1 (0.55) | ALDH1A1ALOX15TDP1GABRA1GABRB2 | |
| SCHEMBL28119481 | 0.84 | GABRA1 (0.55) | ALDH1A1ALOX15TDP1GABRA1GABRB2 | |
| SCHEMBL11412672 | 0.82 | GABRA1 (0.52) | ALDH1A1ALOX15TDP1GABRA1GABRB2 | |
| SCHEMBL26607076 | 0.81 | GABRA1 (0.46) | ALDH1A1ALOX15TDP1GABRA1GABRB2 | |
| Phthalic Acid SCHEMBL28978789 | 0.80 | ALDH1A1 (0.51) | ALDH1A1ALOX15TDP1HPGDHSD17B10 | |
| Phthalic Acid SCHEMBL28978786 | 0.80 | ALDH1A1 (0.51) | ALDH1A1ALOX15TDP1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9133286-B2 | Production of substituted phenylene dibenzoate internal electron donor and procatalyst with same | W. R. GRACE & CO.-CONN (US) | 2015-09-15 | — | — | US | claimed |
| EP-2751063-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE DIBENZOATE FOR USE AS INTERNAL ELECTRON DONOR AND PROCATALYST FOR POLYMER PREPARATION | W.R. GRACE & CO.-CONN. (US) | 2014-07-09 | — | — | EP | claimed |
| EP-2691363-A2 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | Dow Global Technologies LLC (US) | 2014-02-05 | — | — | EP | claimed |
| US-20140012035-A1 | Production of Substituted Phenylene Aromatic Diesters | W.R. GRACE & CO.-CONN. | 2014-01-09 | — | — | US | claimed |
| US-8507717-B2 | Production of substituted phenylene aromatic diesters | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-08-13 | — | — | US | claimed |
| WO-2013032651-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE DIBENZOATE FOR USE AS INTERNAL ELECTRON DONOR AND PROCATALYST FOR POLYMER PREPARATION | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-03-07 | — | — | WO | claimed |
| US-20130053525-A1 | Production of Substituted Phenylene Dibenzoate Internal Electron Donor and Procatalyst with Same | W. R. GRACE & CO.-CONN. | 2013-02-28 | — | — | US | claimed |
| WO-2012135189-A2 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-10-04 | — | — | WO | claimed |
| EP-2373604-A2 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | Dow Global Technologies LLC (US) | 2011-10-12 | — | — | EP | claimed |
| WO-2010078512-A2 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | claimed |
| US-20100174105-A1 | Production of Substituted Phenylene Aromatic Diesters | W.R. GRACE & CO.-CONN. | 2010-07-08 | — | — | US | claimed |
| CN-120483875-B | Process for the preparation of substituted phenylene aromatic diesters and use thereof in the preparation of catalysts | 营口市向阳催化剂有限责任公司 | 2025-10-21 | — | — | CN | disclosed |
| US-20250282897-A1 | PROCESS FOR MAKING A SOLID CATALYST COMPONENT FOR ETHYLENE POLYMERIZATION AND CO-POLYMERIZATION WITH HIGH ACTIVITY AND IMPROVED REACTOR OPERABILITY | FORMOSA PLASTICS CORP USA (US) | 2025-09-11 | — | — | US | disclosed |
| CN-120483875-A | Process for the preparation of substituted phenylene aromatic diesters and use thereof in the preparation of catalysts | 营口市向阳催化剂有限责任公司 | 2025-08-15 | — | — | CN | disclosed |
| US-20250115687-A1 | PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS | FORMOSA PLASTICS CORP USA (US) | 2025-04-10 | — | — | US | disclosed |
| WO-2010078519-A1 | PRODUCTION OF SUBSTITUTED PHENYLENE AROMATIC DIESTERS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-07-08 | — | — | WO | disclosed |
| CN-101313021-A | Radiation absorbing compositions, methods and articles made by applying such compositions | MILLIKEN & CO (US) | 2008-11-26 | — | — | CN | disclosed |
| US-6242514-B1 | CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 2001-06-05 | — | — | US | disclosed |
| US-5306591-A | Higher mobility; improved development and transfer | XEROX CORPORATION (US) | 1994-04-26 | — | — | US | disclosed |
| US-4050945-A | METALLIC COMPOUND REACTANT, CHELATING COMPOUND REACTANT, BINDER | SUZUKI YOSHIO | 1977-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174105-A1 | Production of Substituted Phenylene Aromatic Diesters | DDT, COMT, DDC | ALDH1A1 519/4885ALOX15 2736/4885TDP1 399/4885 |
| US-20140012035-A1 | Production of Substituted Phenylene Aromatic Diesters | PAH, HPD, COMT | ALDH1A1 354/4885ALOX15 2393/4885TDP1 934/4885 |
| US-20130053525-A1 | Production of Substituted Phenylene Dibenzoate Internal Electron Donor and Procatalyst with Same | BMP4, BMP1, BMP2 | ALDH1A1 674/4885ALOX15 833/4885TDP1 823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.