Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.34 |
| ▸ | GABRE | P78334 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28638529 | 0.82 | GABRP (0.44) | TSHRTP53EGLN1EGLN3GABRP | |
| SCHEMBL2727 | 0.72 | TSHR (0.67) | ACHEBACE1MASP2F2TSHR | |
| SCHEMBL30554051 | 0.72 | TSHR (0.67) | ACHEBACE1MASP2F2TSHR | |
| SCHEMBL509417 | 0.72 | TSHR (0.67) | ACHEBACE1MASP2F2TSHR | |
| SCHEMBL2726 | 0.72 | TSHR (0.67) | ACHEBACE1MASP2F2TSHR | |
| SCHEMBL820982 | 0.72 | TSHR (0.67) | ACHEBACE1MASP2F2TSHR | |
| SCHEMBL351491 | 0.72 | TSHR (0.67) | ACHEBACE1MASP2F2TSHR | |
| SCHEMBL30694696 | 0.72 | TSHR (0.67) | ACHEBACE1MASP2F2TSHR | |
| SCHEMBL14600850 | 0.70 | ACHE (0.48) | ACHEBACE1MASP2F2TSHR | |
| SCHEMBL14600849 | 0.70 | ACHE (0.48) | ACHEBACE1MASP2F2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543317-A | GENE WHICH ENCODES A POLYPEPTIDE | FLORIDA WEST, UNIVERSITY OF | 1996-08-06 | — | — | US | disclosed |