Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.48 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990669 | 0.79 | ALDH1A1 (0.50) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8990698 | 0.72 | ALDH1A1 (0.48) | KMT2ARAB9ANPC1SMN1; SMN2TP53 | |
| SCHEMBL6633618 | 0.71 | KMT2A (0.89) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL655417 | 0.70 | RAB9A (0.51) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8990610 | 0.70 | NPC1 (0.52) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5691252 | 0.68 | RAB9A (0.71) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5692749 | 0.68 | NPC1 (0.52) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL5260773 | 0.67 | KMT2A (0.52) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28928871 | 0.67 | RAB9A (0.67) | MEN1KMT2ARAB9ASMN1; SMN2TP53 | |
| SCHEMBL5691055 | 0.66 | RAB9A (0.63) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5500428-A | Furyl-substituted purines and adenosine antagonists | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1996-03-19 | — | — | US | disclosed |
| US-5300509-A | Adenosine antagonists for treating cardiovascular disorders, vasodilation | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1994-04-05 | — | — | US | disclosed |
| EP-0544445-A2 | Furyl-substituted purines, oxazolopyrimidines and pteridines as adenosine antagonists | ZENECA LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |