Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | EEF2K | O00418 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990872 | 0.92 | GHSR (0.40) | HDAC3HDAC1HDAC2AGTR1GHSR | |
| SCHEMBL8990996 | 0.91 | KMT2A (0.38) | AGTR1GHSRNPSR1KMT2ANAMPT | |
| SCHEMBL8990882 | 0.90 | ADRB2 (0.35) | HDAC3HDAC1HDAC2NPSR1KMT2A | |
| SCHEMBL8991085 | 0.90 | ADRB2 (0.38) | HDAC3HDAC1HDAC2NPSR1KMT2A | |
| SCHEMBL8990990 | 0.88 | GHSR (0.38) | HDAC1AGTR1GHSRNPSR1KMT2A | |
| SCHEMBL8990909 | 0.86 | GHSR (0.38) | HDAC1AGTR1GHSRKMT2AALDH1A1 | |
| SCHEMBL8990905 | 0.84 | TSHR (0.37) | HDAC3HDAC1HDAC2AGTR1GHSR | |
| SCHEMBL8990950 | 0.82 | ADRB2 (0.33) | HDAC1AGTR1GHSRNPSR1KMT2A | |
| SCHEMBL8990892 | 0.82 | ADRB2 (0.31) | NAMPTROCK2ALDH1A1TSHR | |
| SCHEMBL8990940 | 0.82 | KMT2A (0.35) | NPSR1KMT2ATP53ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |