Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | EEF2K | O00418 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991085 | 0.95 | ADRB2 (0.38) | ADRB2ADRB1ADRB3NPSR1KMT2A | |
| SCHEMBL8990950 | 0.93 | ADRB2 (0.33) | ADRB2ADRB1ADRB3NPSR1KMT2A | |
| SCHEMBL8990940 | 0.92 | KMT2A (0.35) | ADRB2ADRB1ADRB3NPSR1KMT2A | |
| SCHEMBL8990892 | 0.92 | ADRB2 (0.31) | ADRB2ADRB1ADRB3NAMPTROCK2 | |
| SCHEMBL8990769 | 0.90 | HDAC3 (0.36) | NPSR1KMT2AHDAC3HDAC1HDAC2 | |
| SCHEMBL8990719 | 0.89 | SMN1; SMN2 (0.34) | NPSR1KMT2ALMNAALDH1A1GAA | |
| SCHEMBL8990964 | 0.88 | GHSR (0.34) | KMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8990830 | 0.87 | ADRB2 (0.36) | ADRB2ADRB1ADRB3HDAC1NAMPT | |
| SCHEMBL8990896 | 0.87 | ADRB2 (0.33) | ADRB2ADRB1ADRB3NAMPTROCK2 | |
| SCHEMBL8990868 | 0.87 | KMT2A (0.34) | ADRB2ADRB1ADRB3NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |