Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GHSR | Q92847 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990872 | 0.92 | GHSR (0.40) | TSHRALDH1A1GHSRGAAHDAC1 | |
| SCHEMBL8990950 | 0.86 | ADRB2 (0.33) | TSHRALDH1A1GHSRGAAHDAC1 | |
| SCHEMBL8990830 | 0.85 | ADRB2 (0.36) | TSHRALDH1A1GHSRGAAHDAC1 | |
| SCHEMBL8990769 | 0.84 | HDAC3 (0.36) | TSHRALDH1A1GHSRGAAHDAC1 | |
| SCHEMBL8990915 | 0.84 | GHSR (0.48) | ALDH1A1GHSRHDAC1SMN1; SMN2KMT2A | |
| SCHEMBL8990996 | 0.83 | KMT2A (0.38) | ALDH1A1GHSRMAPTKDM4ENAMPT | |
| SCHEMBL8990776 | 0.82 | GHSR (0.47) | GHSRHDAC1SMN1; SMN2KMT2AAGTR1 | |
| SCHEMBL8990882 | 0.79 | ADRB2 (0.35) | TSHRALDH1A1GAAHDAC1HDAC3 | |
| SCHEMBL8990974 | 0.78 | GHSR (0.45) | ALDH1A1GHSRHDAC1KMT2AAGTR1 | |
| SCHEMBL8990979 | 0.78 | GHSR (0.51) | GHSRHDAC1KMT2AAGTR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |