Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 2/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | PTGFR | P43088 | 2/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.33 |
| ▸ | PTGIR | P43119 | 2/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990979 | 0.91 | GHSR (0.51) | GHSRAGTR1GRM2HDAC1KMT2A | |
| SCHEMBL8990951 | 0.89 | GHSR (0.61) | GHSRAGTR1GRM2HDAC1KMT2A | |
| SCHEMBL8990886 | 0.89 | GHSR (0.50) | GHSRAGTR1GRM2HDAC1KMT2A | |
| SCHEMBL8990983 | 0.89 | GHSR (0.62) | GHSRAGTR1GRM2HDAC1KMT2A | |
| SCHEMBL8990941 | 0.88 | GHSR (0.62) | GHSRAGTR1GRM2HDAC1HDAC7 | |
| SCHEMBL8990967 | 0.85 | GHSR (0.45) | GHSRAGTR1HDAC1KMT2AMEN1 | |
| SCHEMBL8990974 | 0.85 | GHSR (0.45) | GHSRAGTR1HDAC1KMT2AMEN1 | |
| SCHEMBL8990919 | 0.84 | GHSR (0.40) | GHSRAGTR1GRM2HDAC1KMT2A | |
| SCHEMBL8990975 | 0.84 | GHSR (0.45) | GHSRAGTR1GRM2HDAC1KMT2A | |
| SCHEMBL8990879 | 0.84 | GHSR (0.52) | GHSRAGTR1HDAC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |