Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.61 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990983 | 0.93 | GHSR (0.62) | GHSRAGTR1MCHR1XIAPLIPG | |
| SCHEMBL8990941 | 0.92 | GHSR (0.62) | GHSRAGTR1MCHR1LIPGPTGER1 | |
| SCHEMBL8990979 | 0.92 | GHSR (0.51) | GHSRAGTR1XIAPLIPGPTGER1 | |
| SCHEMBL8990991 | 0.92 | GHSR (0.54) | GHSRAGTR1MCHR1XIAPLIPG | |
| SCHEMBL8990935 | 0.91 | GHSR (0.55) | GHSRMCHR1LIPGMEN1KMT2A | |
| SCHEMBL8990886 | 0.91 | GHSR (0.50) | GHSRAGTR1MCHR1LIPGTHRB | |
| SCHEMBL8990807 | 0.90 | GHSR (0.54) | GHSRAGTR1MCHR1KMT2A | |
| SCHEMBL8990821 | 0.90 | GHSR (0.54) | GHSRMCHR1XIAPMEN1KMT2A | |
| SCHEMBL8990776 | 0.89 | GHSR (0.47) | GHSRAGTR1XIAPPTGER1PTGER3 | |
| SCHEMBL8990975 | 0.86 | GHSR (0.45) | GHSRAGTR1PTGER1PTGER3GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |