Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990979 | 0.92 | GHSR (0.51) | GHSRAGTR1KMT2AKCNA5MEN1 | |
| SCHEMBL8990858 | 0.92 | GHSR (0.43) | GHSRAGTR1KMT2ASMN1; SMN2KCNA5 | |
| SCHEMBL8990951 | 0.91 | GHSR (0.61) | GHSRAGTR1KMT2AMEN1LIPG | |
| SCHEMBL8990983 | 0.90 | GHSR (0.62) | GHSRAGTR1KMT2AMEN1LIPG | |
| SCHEMBL8990776 | 0.89 | GHSR (0.47) | GHSRAGTR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8990941 | 0.89 | GHSR (0.62) | GHSRAGTR1LIPGTHRBMCHR1 | |
| SCHEMBL8991005 | 0.85 | GHSR (0.55) | GHSRAGTR1KMT2AMEN1BDKRB1 | |
| SCHEMBL8990801 | 0.85 | GHSR (0.39) | GHSRAGTR1KMT2AKCNA5MEN1 | |
| SCHEMBL8990924 | 0.85 | GHSR (0.45) | GHSRKMT2ASMN1; SMN2KCNA5MEN1 | |
| SCHEMBL8990750 | 0.84 | GHSR (0.39) | GHSRAGTR1KMT2AKCNA5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |