Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.51 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990886 | 0.92 | GHSR (0.50) | GHSRAGTR1LIPGTHRBGRM2 | |
| SCHEMBL8990951 | 0.92 | GHSR (0.61) | GHSRAGTR1LIPGTHRBGRM2 | |
| SCHEMBL8990983 | 0.91 | GHSR (0.62) | GHSRAGTR1LIPGTHRBGRM2 | |
| SCHEMBL8990887 | 0.91 | GHSR (0.46) | GHSRLIPGGRM2MEN1KMT2A | |
| SCHEMBL8990776 | 0.91 | GHSR (0.47) | GHSRAGTR1GRM2HDAC1HDAC7 | |
| SCHEMBL8990941 | 0.91 | GHSR (0.62) | GHSRAGTR1LIPGTHRBGRM2 | |
| SCHEMBL8990924 | 0.89 | GHSR (0.45) | GHSRMEN1KMT2AKCNA5KCNH2 | |
| SCHEMBL8990840 | 0.85 | GHSR (0.41) | GHSRAGTR1XIAPBACE1 | |
| SCHEMBL8991054 | 0.85 | GHSR (0.56) | GHSRAGTR1 | |
| SCHEMBL8990997 | 0.85 | GHSR (0.40) | GHSRAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |