Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990788 | 0.94 | GHSR (0.47) | GHSRAGTR1SIGMAR1 | |
| SCHEMBL8991057 | 0.90 | GHSR (0.40) | GHSRAGTR1SIGMAR1FFAR1FFAR4 | |
| SCHEMBL8991001 | 0.90 | GHSR (0.42) | GHSR | |
| SCHEMBL8990807 | 0.86 | GHSR (0.54) | GHSRAGTR1FFAR1FFAR4 | |
| SCHEMBL8990735 | 0.85 | GHSR (0.44) | GHSR | |
| SCHEMBL8990795 | 0.84 | GHSR (0.43) | GHSR | |
| SCHEMBL8990767 | 0.84 | GHSR (0.48) | GHSRAGTR1SIGMAR1 | |
| SCHEMBL8990793 | 0.84 | GHSR (0.38) | GHSRAGTR1SIGMAR1 | |
| SCHEMBL8990904 | 0.84 | GHSR (0.42) | GHSR | |
| SCHEMBL8990888 | 0.84 | AGTR1 (0.35) | GHSRAGTR1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |