Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990938 | 0.94 | GHSR (0.48) | GHSRAGTR1SIGMAR1 | |
| SCHEMBL8990807 | 0.92 | GHSR (0.54) | GHSRAGTR1MCHR1 | |
| SCHEMBL8991057 | 0.91 | GHSR (0.40) | GHSRAGTR1SIGMAR1 | |
| SCHEMBL8990767 | 0.90 | GHSR (0.48) | GHSRAGTR1MCHR1SIGMAR1 | |
| SCHEMBL8990991 | 0.90 | GHSR (0.54) | GHSRAGTR1MCHR1 | |
| SCHEMBL8990904 | 0.90 | GHSR (0.42) | GHSR | |
| SCHEMBL8990793 | 0.89 | GHSR (0.38) | GHSRAGTR1SIGMAR1 | |
| SCHEMBL8990888 | 0.85 | AGTR1 (0.35) | GHSRAGTR1SIGMAR1 | |
| SCHEMBL8990845 | 0.85 | GHSR (0.37) | GHSRAGTR1SIGMAR1 | |
| SCHEMBL8990735 | 0.84 | GHSR (0.44) | GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |