Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.54 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990788 | 0.92 | GHSR (0.47) | GHSRMCHR1AGTR1 | |
| SCHEMBL8990935 | 0.90 | GHSR (0.55) | GHSRMCHR1KMT2A | |
| SCHEMBL8990951 | 0.90 | GHSR (0.61) | GHSRMCHR1KMT2AAGTR1 | |
| SCHEMBL8990821 | 0.89 | GHSR (0.54) | GHSRMCHR1KMT2A | |
| SCHEMBL8990927 | 0.86 | GHSR (0.58) | GHSRMCHR1KMT2AAGTR1 | |
| SCHEMBL8990904 | 0.86 | GHSR (0.42) | GHSR | |
| SCHEMBL8990938 | 0.86 | GHSR (0.48) | GHSRFFAR1FFAR4AGTR1 | |
| SCHEMBL8991036 | 0.84 | GHSR (0.40) | GHSRKMT2AAGTR1 | |
| SCHEMBL8991040 | 0.84 | GHSR (0.40) | GHSRKMT2AAGTR1 | |
| SCHEMBL8990780 | 0.84 | GHSR (0.56) | GHSRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |