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SCHEMBL8990891

SCHEMBL8990891

CSc1ccc2c(c1)S[C@@H](NC(=O)CC(C)(C)NC[C@H](O)CO)C(=O)N(Cc1ccc(-c3ccccc3CNC(N)=O)cc1)C2

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 4/20 0.36
▸ AGTR1 P30556 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8990747 0.94 GHSR (0.36) GHSRAGTR1
SCHEMBL8991001 0.93 GHSR (0.42) GHSR
SCHEMBL8990795 0.93 GHSR (0.43) GHSR
SCHEMBL8990853 0.91 GHSR (0.37) GHSRAGTR1
SCHEMBL8990997 0.91 GHSR (0.40) GHSRAGTR1
SCHEMBL8990904 0.88 GHSR (0.42) GHSR
SCHEMBL8990735 0.87 GHSR (0.44) GHSR
SCHEMBL8991081 0.86 GHSR (0.33) GHSR
SCHEMBL8990749 0.86 GHSR (0.31) GHSR
SCHEMBL8990840 0.85 GHSR (0.41) GHSRAGTR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5545735-A ANIMAL GROWTH REGULATORS MERCK & CO., INC. (US) 1996-08-13 — — US claimed
US-5545735-A ANIMAL GROWTH REGULATORS MERCK & CO., INC. (US) 1996-08-13 — — US disclosed