Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990986 | 0.92 | AGTR1 (0.47) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8990728 | 0.91 | GHSR (0.42) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8991075 | 0.91 | GHSR (0.46) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8991073 | 0.91 | AGTR1 (0.46) | GHSRAGTR1TACR1 | |
| SCHEMBL9024343 | 0.88 | GHSR (0.65) | GHSRAGTR1 | |
| SCHEMBL8990984 | 0.88 | AGTR1 (0.41) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8990977 | 0.87 | AGTR1 (0.40) | GHSRAGTR1TACR1OPRM1OPRD1 | |
| SCHEMBL8990860 | 0.86 | GHSR (0.48) | GHSRAGTR1 | |
| SCHEMBL9694552 | 0.86 | GHSR (0.48) | GHSRAGTR1 | |
| SCHEMBL8991039 | 0.85 | AGTR1 (0.41) | GHSRAGTR1TACR1OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |