Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | GHSR | Q92847 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990984 | 0.94 | AGTR1 (0.41) | AGTR1GHSRTACR1MMEACE | |
| SCHEMBL8990738 | 0.93 | AGTR1 (0.36) | AGTR1GHSRTACR1OPRM1FNTA | |
| SCHEMBL8991115 | 0.92 | AGTR1 (0.36) | AGTR1GHSR | |
| SCHEMBL8991106 | 0.92 | AGTR1 (0.36) | AGTR1GHSR | |
| SCHEMBL8990937 | 0.87 | AGTR1 (0.38) | AGTR1GHSR | |
| SCHEMBL8990854 | 0.87 | GHSR (0.52) | AGTR1GHSRTACR1MMEACE | |
| SCHEMBL8990922 | 0.87 | AGTR1 (0.37) | AGTR1GHSRTACR1OPRM1OPRD1 | |
| SCHEMBL8990851 | 0.86 | TACR1 (0.38) | AGTR1GHSRTACR1MMEACE | |
| SCHEMBL8991098 | 0.86 | AGTR1 (0.36) | AGTR1GHSR | |
| SCHEMBL8990756 | 0.86 | AGTR1 (0.36) | AGTR1GHSRTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |