SCHEMBL8991081

SCHEMBL8991081

CSc1ccc2c(c1)S[C@@H](NC(=O)CC(C)(C)NC[C@H](O)CO)C(=O)N(Cc1ccc(-c3ccccc3NC(=O)NCCO)cc1)C2

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8990978 0.94 GHSR (0.34) GHSR
SCHEMBL8990749 0.94 GHSR (0.31) GHSR
SCHEMBL8991052 0.93
SCHEMBL8990981 0.92 GHSR (0.34) GHSR
SCHEMBL8990726 0.91 GHSR (0.37) GHSR
SCHEMBL8990795 0.91 GHSR (0.43) GHSR
SCHEMBL8991053 0.90 GHSR (0.33) GHSR
SCHEMBL8990845 0.90 GHSR (0.37) GHSR
SCHEMBL8990875 0.88 GHSR (0.31) GHSR
SCHEMBL8990896 0.88 ADRB2 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5545735-A ANIMAL GROWTH REGULATORS MERCK & CO., INC. (US) 1996-08-13 US claimed