SCHEMBL8991001

SCHEMBL8991001

CCNC(=O)NCc1ccccc1-c1ccc(CN2Cc3ccc(SC)cc3S[C@@H](NC(=O)CC(C)(C)NC[C@H](O)CO)C2=O)cc1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GHSR Q92847 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8990795 0.95 GHSR (0.43) GHSR
SCHEMBL8990891 0.93 GHSR (0.36) GHSR
SCHEMBL8990957 0.92 GHSR (0.43) GHSR
SCHEMBL8990751 0.91 GHSR (0.47) GHSR
SCHEMBL8991009 0.91 GHSR (0.42) GHSR
SCHEMBL8990735 0.90 GHSR (0.44) GHSR
SCHEMBL8990938 0.90 GHSR (0.48) GHSR
SCHEMBL8990904 0.89 GHSR (0.42) GHSR
SCHEMBL8990806 0.88 GHSR (0.43) GHSR
SCHEMBL8990747 0.87 GHSR (0.36) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5545735-A ANIMAL GROWTH REGULATORS MERCK & CO., INC. (US) 1996-08-13 US claimed
US-5545735-A ANIMAL GROWTH REGULATORS MERCK & CO., INC. (US) 1996-08-13 US disclosed