Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 7/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | PYGL | P06737 | 1/20 | 0.34 |
| ▸ | PYGM | P11217 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991073 | 0.92 | AGTR1 (0.46) | GHSRAGTR1ROCK1ROCK2NAMPT | |
| SCHEMBL8990728 | 0.90 | GHSR (0.42) | GHSRAGTR1 | |
| SCHEMBL8991104 | 0.90 | GHSR (0.38) | GHSRAGTR1ROCK1ROCK2 | |
| SCHEMBL8991149 | 0.89 | GHSR (0.37) | GHSRAGTR1 | |
| SCHEMBL8991098 | 0.85 | AGTR1 (0.36) | GHSRAGTR1ROCK1ROCK2NAMPT | |
| SCHEMBL8991106 | 0.85 | AGTR1 (0.36) | GHSRAGTR1ROCK1ROCK2NAMPT | |
| SCHEMBL8990865 | 0.83 | GHSR (0.44) | GHSRROCK2NAMPTSCN9AXIAP | |
| SCHEMBL8990912 | 0.82 | HDAC1 (0.34) | GHSRAGTR1 | |
| SCHEMBL8990986 | 0.82 | AGTR1 (0.47) | GHSRAGTR1ROCK1ROCK2 | |
| SCHEMBL8990854 | 0.82 | GHSR (0.52) | GHSRAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |