Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.36 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991098 | 0.94 | AGTR1 (0.36) | AGTR1GHSRROCK1XIAPROCK2 | |
| SCHEMBL8990977 | 0.92 | AGTR1 (0.40) | AGTR1GHSR | |
| SCHEMBL8990738 | 0.91 | AGTR1 (0.36) | AGTR1GHSRROCK1ROCK2 | |
| SCHEMBL8991115 | 0.90 | AGTR1 (0.36) | AGTR1GHSR | |
| SCHEMBL8991073 | 0.88 | AGTR1 (0.46) | AGTR1GHSRROCK1ROCK2NAMPT | |
| SCHEMBL8990917 | 0.88 | AGTR1 (0.34) | AGTR1GHSRROCK1 | |
| SCHEMBL8990984 | 0.86 | AGTR1 (0.41) | AGTR1GHSR | |
| SCHEMBL8990922 | 0.85 | AGTR1 (0.37) | AGTR1GHSRROCK1ROCK2 | |
| SCHEMBL8991080 | 0.85 | FPR2 (0.35) | AGTR1GHSRXIAPROCK2NAMPT | |
| SCHEMBL8990895 | 0.85 | GHSR (0.37) | AGTR1GHSRROCK1XIAPROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |