Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 2/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | DRD4 | P21917 | 5/20 | 0.36 |
| ▸ | DRD3 | P35462 | 5/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | DRD1 | P21728 | 2/20 | 0.34 |
| ▸ | DRD5 | P21918 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990947 | 0.93 | GHSR (0.38) | GHSRAGTR1FPR1FPR2KMT2A | |
| SCHEMBL8990909 | 0.91 | GHSR (0.38) | GHSRAGTR1DRD2DRD4DRD3 | |
| SCHEMBL8991050 | 0.91 | GHSR (0.34) | GHSRDRD2DRD4DRD3FPR1 | |
| SCHEMBL8990880 | 0.90 | GHSR (0.42) | GHSRAGTR1DRD2DRD4DRD3 | |
| SCHEMBL8991053 | 0.90 | GHSR (0.33) | GHSRDRD2DRD4DRD3FPR1 | |
| SCHEMBL8990845 | 0.89 | GHSR (0.37) | GHSRAGTR1DRD2DRD4DRD3 | |
| SCHEMBL8990996 | 0.86 | KMT2A (0.38) | GHSRAGTR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8991065 | 0.84 | GHSR (0.39) | GHSRAGTR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL8990943 | 0.84 | FPR1 (0.34) | GHSRFPR1FPR2KMT2AALDH1A1 | |
| SCHEMBL8990826 | 0.83 | FPR1 (0.34) | GHSRFPR1FPR2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| WO-1995009633-A1 | BENZO-FUSED LACTAMS PROMOTE RELEASE OF GROWTH HORMONE | MERCK & CO., INC. (US) | 1995-04-13 | — | — | WO | disclosed |