Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 1/20 | 0.33 |
| ▸ | FPR1 | P21462 | 1/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 4/20 | 0.32 |
| ▸ | DRD4 | P21917 | 4/20 | 0.32 |
| ▸ | DRD3 | P35462 | 4/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SDCBP | O00560 | 1/20 | 0.31 |
| ▸ | SDC2 | P34741 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | DRD1 | P21728 | 1/20 | 0.30 |
| ▸ | DRD5 | P21918 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991050 | 0.94 | GHSR (0.34) | GHSRFPR1FPR2PDE10ADRD2 | |
| SCHEMBL8990826 | 0.94 | FPR1 (0.34) | GHSRFPR1FPR2KMT2ANPSR1 | |
| SCHEMBL8990981 | 0.92 | GHSR (0.34) | GHSRFPR1FPR2DRD2DRD4 | |
| SCHEMBL8990726 | 0.91 | GHSR (0.37) | GHSRDRD2DRD4DRD3 | |
| SCHEMBL8991081 | 0.90 | GHSR (0.33) | GHSR | |
| SCHEMBL8991006 | 0.90 | GHSR (0.37) | GHSRFPR1FPR2PDE10ADRD2 | |
| SCHEMBL8990943 | 0.88 | FPR1 (0.34) | GHSRFPR1FPR2KMT2ANPSR1 | |
| SCHEMBL8990868 | 0.88 | KMT2A (0.34) | FPR1FPR2KMT2ANPSR1MAPT | |
| SCHEMBL8991009 | 0.86 | GHSR (0.42) | GHSRDRD2DRD4DRD3KMT2A | |
| SCHEMBL8990964 | 0.86 | GHSR (0.34) | GHSRFPR1FPR2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |