Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK5 | O95279 | 1/20 | 0.33 |
| ▸ | KCNK17 | Q96T54 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990924 | 0.92 | GHSR (0.45) | GHSRKCNA5KCNH2PLA2G2ASIGMAR1 | |
| SCHEMBL8990858 | 0.86 | GHSR (0.43) | GHSRAGTR1KCNA5HTR7MEN1 | |
| SCHEMBL8990821 | 0.85 | GHSR (0.54) | GHSRKCNA5KCNH2PLA2G2AHTR7 | |
| SCHEMBL8990947 | 0.85 | GHSR (0.38) | GHSRAGTR1SIGMAR1KMT2AALDH1A1 | |
| SCHEMBL8990822 | 0.85 | GHSR (0.55) | GHSRKCNA5KCNH2PLA2G2AMEN1 | |
| SCHEMBL8991006 | 0.84 | GHSR (0.37) | GHSRAGTR1SIGMAR1MEN1KMT2A | |
| SCHEMBL8990929 | 0.84 | GHSR (0.55) | GHSRKCNA5KCNH2PLA2G2AMEN1 | |
| SCHEMBL8990767 | 0.83 | GHSR (0.48) | GHSRAGTR1KCNA5KCNH2SIGMAR1 | |
| SCHEMBL8990877 | 0.83 | GHSR (0.42) | GHSRKCNA5KCNH2PLA2G2AMEN1 | |
| SCHEMBL8991060 | 0.83 | GHSR (0.44) | GHSRKCNA5KCNH2PLA2G2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |