Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | RET | P07949 | 6/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | PI4KA | P42356 | 1/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.38 |
| ▸ | FYN | P06241 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695931 | 0.88 | ADK (0.46) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL7698503 | 0.88 | HTT (0.43) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL8991292 | 0.88 | ADORA2A (0.51) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL8991089 | 0.87 | EGFR (0.45) | SRCRIPK2PI4KAPI4K2BPI4K2A | |
| SCHEMBL8991269 | 0.87 | PI4KA (0.39) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL8991101 | 0.86 | RIPK2 (0.42) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL8991063 | 0.85 | GAA (0.41) | TP53SRCMAPTLMNAALDH1A1 | |
| SCHEMBL8991245 | 0.81 | SRC (0.40) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL7698505 | 0.78 | FYN (0.39) | KDM4EMAPK1HTTTSHRHSD17B10 | |
| SCHEMBL8991031 | 0.78 | KDM4E (0.41) | KDM4EMAPK1HTTTSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |