Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 3/20 | 0.51 |
| ▸ | PI4KA | P42356 | 1/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 9/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | ABL2 | P42684 | 4/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991019 | 0.88 | KDM4E (0.41) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7696370 | 0.87 | ADORA2A (0.51) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL7701218 | 0.87 | RET (0.52) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8991101 | 0.86 | RIPK2 (0.42) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8991269 | 0.84 | PI4KA (0.39) | PI4KAPI4K2BPI4K2API4KBRET | |
| SCHEMBL8991270 | 0.84 | IGF1R (0.43) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL8991089 | 0.84 | EGFR (0.45) | PI4KAPI4K2BPI4K2API4KBSRC | |
| SCHEMBL8991245 | 0.83 | SRC (0.40) | MAPK1KDM4ETSHRHTTHSD17B10 | |
| SCHEMBL8991388 | 0.83 | PDE4A (0.50) | ADORA2API4KAPI4K2BPI4K2API4KB | |
| SCHEMBL17406879 | 0.79 | KDM4E (0.59) | ADORA2API4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |