Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 4/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7695714 | 0.89 | ADRA1D (0.51) | RIPK2SRCABL1EIF2AK3ADRA1D | |
| SCHEMBL7697684 | 0.89 | ADRA1D (0.41) | RIPK2SRCABL1EIF2AK3ADRA1D | |
| SCHEMBL8991019 | 0.86 | KDM4E (0.41) | RIPK2SRCABL1EIF2AK3TP53 | |
| SCHEMBL8991292 | 0.86 | ADORA2A (0.51) | SRCABL1KDM4EHTTHSD17B10 | |
| SCHEMBL8991105 | 0.81 | EIF2AK3 (0.42) | RIPK2SRCABL1EIF2AK3ADRA1D | |
| SCHEMBL7697687 | 0.80 | RIPK1 (0.42) | RIPK2SRCABL1EIF2AK3ADRA1D | |
| SCHEMBL8991245 | 0.80 | SRC (0.40) | RIPK2SRCABL1EIF2AK3KDM4E | |
| SCHEMBL8991269 | 0.79 | PI4KA (0.39) | SRCABL1KDM4EHTTHSD17B10 | |
| SCHEMBL8991089 | 0.79 | EGFR (0.45) | RIPK2SRCABL1KDREGFR | |
| SCHEMBL7703250 | 0.79 | CFD (0.42) | RIPK2SRCABL1EIF2AK3KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |