Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 6/20 | 0.40 |
| ▸ | EGFR | P00533 | 3/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | ABL2 | P42684 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700881 | 0.88 | CFD (0.45) | SRCEGFRCDK1PIK3CDKDM4E | |
| SCHEMBL7704461 | 0.88 | HTT (0.42) | SRCEGFRCDK1PIK3CDKDM4E | |
| SCHEMBL8991225 | 0.85 | PDE4A (0.42) | SRCEGFRTSHRHTTABL1 | |
| SCHEMBL8991292 | 0.83 | ADORA2A (0.51) | SRCEGFRCDK1PIK3CDKDM4E | |
| SCHEMBL8991019 | 0.81 | KDM4E (0.41) | SRCEGFRKDM4ETSHRMAPK1 | |
| SCHEMBL8991101 | 0.80 | RIPK2 (0.42) | SRCEGFRCDK1PIK3CDKDM4E | |
| SCHEMBL8991256 | 0.79 | KDM4E (0.40) | SRCEGFRCDK1PIK3CDKDM4E | |
| SCHEMBL7704465 | 0.79 | EIF2AK3 (0.40) | SRCEGFRCDK1PIK3CDKDM4E | |
| SCHEMBL7702542 | 0.78 | CFD (0.43) | SRCEGFRCDK1PIK3CDKDM4E | |
| SCHEMBL8991123 | 0.77 | KDM4E (0.44) | SRCEGFRCDK1PIK3CDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |