Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10750142 | 0.87 | MAPT (0.34) | TSHRALDH1A1RAB9A | |
| SCHEMBL10489117 | 0.80 | LTA4H (0.41) | TSHRLTA4HALDH1A1CA4KCNA3 | |
| SCHEMBL8993692 | 0.80 | TSHR (0.41) | TSHRLTA4HALDH1A1CA4KCNA3 | |
| SCHEMBL4532633 | 0.80 | ALDH1A1 (0.43) | TSHRLTA4HALDH1A1CA4KCNA3 | |
| SCHEMBL8649157 | 0.79 | PPARA (0.42) | TSHR | |
| SCHEMBL10641834 | 0.79 | GAA (0.40) | ALDH1A1 | |
| SCHEMBL10750134 | 0.78 | CA12 (0.32) | TSHRALDH1A1CA4 | |
| SCHEMBL9870824 | 0.77 | TSHR (0.37) | TSHRKIF11 | |
| SCHEMBL10603953 | 0.76 | TSHR (0.38) | TSHRLTA4HALDH1A1CA4KCNA3 | |
| SCHEMBL15153656 | 0.76 | TSHR (0.38) | TSHRLTA4HALDH1A1CA4KCNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4643811-A | PHOTOCHLORINATION | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1987-02-17 | — | — | US | claimed |
| EP-0567847-B1 | Halogenation process in advantageous solvents | BAYER AG (DE) | 1996-09-18 | — | — | EP | disclosed |
| EP-0567848-B1 | Process for the alpha-chlorination of arylethern | BAYER AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| US-5484932-A | Halogenation processes in advantageous solvents, and novel bistrifluoromethyl-polyfluoroalkoxybenzenes | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-16 | — | — | US | disclosed |
| US-5300201-A | Mixing with chlorine, irradiating; selective formation of 4-chloro phthalic anhydride | OCCIDENTAL CHEMICAL CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0567848-A1 | Process for the alpha-chlorination of arylethern | BAYER AG (DE) | 1993-11-03 | — | — | EP | disclosed |
| EP-0567847-A1 | Halogenation process in advantageous solvents | BAYER AG (DE) | 1993-11-03 | — | — | EP | disclosed |
| US-4837364-A | REACTION OF HALOBENZENE WITH TRIFLUOROETHANOL | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1989-06-06 | — | — | US | disclosed |
| EP-0197869-B1 | PROCESS FOR THE PREPARATION OF PENTAFLUOROETHOXY- AND PENTAFLUOROETHYL THIOBENZENE DERIVATIVES | RHONE-POULENC CHIMIE (FR) | 1989-05-31 | — | — | EP | disclosed |
| EP-0199660-B1 | PROCESS FOR THE PREPARATION OF AROMATIC 1,1-DIFLUOROPERHALOALKOXY OR 1,1-DIFLUOROPERHALOTHIOALKYL DERIVATIVES | RHONE-POULENC CHIMIE (FR) | 1989-02-08 | — | — | EP | disclosed |
| EP-0197868-B1 | PROCESS FOR THE PREPARATION OF DICHLOROTRIFLUOROETHOXY AND ETHYLTHIOAROMATIC DERIVATIVES | RHONE-POULENC CHIMIE (FR) | 1988-05-18 | — | — | EP | disclosed |
| US-4727187-A | CATALYTIC FLUORINATION OF DICHLOROALKYL PHENYL ETHER | CIBA-GEIGY CORPORATION (US) | 1988-02-23 | — | — | US | disclosed |
| US-4643811-A | PHOTOCHLORINATION | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1987-02-17 | — | — | US | disclosed |
| US-4643811-A | PHOTOCHLORINATION | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1987-02-17 | — | — | US | disclosed |
| EP-0199660-A1 | Process for the preparation of aromatic 1,1-difluoroperhaloalkoxy or 1,1-difluoroperhalothioalkyl derivatives | RHONE-POULENC CHIMIE (FR) | 1986-10-29 | — | — | EP | disclosed |
| EP-0197869-A1 | Process for the preparation of pentafluoroethoxy- and pentafluoroethyl thiobenzene derivatives | RHONE-POULENC CHIMIE (FR) | 1986-10-15 | — | — | EP | disclosed |