Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | BAX | Q07812 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970585 | 0.86 | KIF11 (0.46) | ALDH1A1KDRABL1KIF11GRIN2B | |
| SCHEMBL8993692 | 0.84 | TSHR (0.41) | ALDH1A1TSHRLTA4HCA5ACA5B | |
| SCHEMBL8991041 | 0.80 | TSHR (0.38) | ALDH1A1TSHRLTA4HCA5ACA5B | |
| SCHEMBL15153656 | 0.80 | TSHR (0.38) | ALDH1A1TSHRLTA4HCA5ACA5B | |
| SCHEMBL10603953 | 0.80 | TSHR (0.38) | ALDH1A1TSHRLTA4HCA5ACA5B | |
| SCHEMBL10731637 | 0.80 | TSHR (0.38) | ALDH1A1TSHRLTA4HCA5ACA5B | |
| SCHEMBL8993672 | 0.78 | KIF11 (0.41) | LTA4HKIF11GRIN2BRAB9A | |
| SCHEMBL168125 | 0.78 | KIF11 (0.47) | TSHRLTA4HKIF11GRIN2BRAB9A | |
| SCHEMBL53548 | 0.78 | TSHR (0.45) | ALDH1A1TSHRLTA4HCA5ACA5B | |
| SCHEMBL2743975 | 0.78 | TSHR (0.45) | ALDH1A1TSHRLTA4HCA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4914244-A | FROM A PHENOL AND TRICHLOROMETHYL CHLOROFORMATE IN THE PRESENCE OF HYDROGEN FLUORIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-04-03 | — | — | US | claimed |
| EP-0239726-B1 | PROCESS FOR THE PRODUCTION OF DIFLUOROCHLOROMETHOXYBENZENES | BAYER AG (DE) | 1989-03-15 | — | — | EP | claimed |
| JP-6263678-A | — | — | None | — | — | JP | disclosed |
| CN-112521254-B | Preparation method of trifluoromethoxybenzene compound | 金凯(辽宁)生命科技股份有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-114149409-B | (hetero) aryl amide compound with protein kinase inhibition activity | 中国药科大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-114539036-B | Method for efficiently synthesizing trichloromethoxybenzene by controlling chlorination depth | 金凯(辽宁)生命科技股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| WO-2023116877-A1 | HETEROCYCLIC COMPOUND AS TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-06-29 | — | — | WO | disclosed |
| CN-114539036-A | Method for efficiently synthesizing trichloromethoxybenzene by controlling chlorination depth | 金凯(辽宁)生命科技股份有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-112521254-A | Preparation method of trifluoromethoxybenzene compound | 金凯(辽宁)生命科技股份有限公司 | 2021-03-19 | — | — | CN | disclosed |
| US-20180133170-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | ELI LILLY AND COMPANY | 2018-05-17 | — | — | US | disclosed |
| CN-104119238-A | Preparation method for 4-(chlorodifluoromethoxy)aniline | KINGCHEM LIAONING CHEMICAL CO LTD | 2014-10-29 | — | — | CN | disclosed |
| EP-0140783-A2 | Process for the preparation of meta-substituted anilines | RHONE-POULENC CHIMIE (FR) | 1985-05-08 | — | — | EP | disclosed |
| EP-0084743-B1 | PROCESS FOR THE PREPARATION OF ALPHA, ALPHA-DIFLUOROALKOXY OR ALPHA, ALPHADIFLUOROALKYLTHIOPHENYL SULFONES | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-11-21 | — | — | EP | disclosed |
| US-4446078-A | REACTING A POLYHALOALKOXY- OR POLYHALOALKYLTHIOBENZENE WITH A CARBOXYLIC DERIVATIVE, BORON TRIFLUORIDE | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-05-01 | — | — | US | disclosed |
| US-4438043-A | Process for preparation of di- or trifluoromethoxyphenyl ketones or di- or trifluoromethylthiophenyl ketones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-03-20 | — | — | US | disclosed |
| EP-0092627-A1 | Process for the preparation of di- or trifluoromethoxyphenyl ketones or of di- or trifluoromethylthiophenyl ketones | RHONE-POULENC CHIMIE (FR) | 1983-11-02 | — | — | EP | disclosed |
| EP-0085265-A1 | Process for the preparation of alpha,alpha-difluoroalkoxy or alpha,alpha-difluoroalkylthiophenyl ketones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-08-10 | — | — | EP | disclosed |
| EP-0084743-A1 | Process for the preparation of alpha, alpha-difluoroalkoxy or alpha, alphadifluoroalkylthiophenyl sulfones | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-08-03 | — | — | EP | disclosed |
| EP-0084128-A1 | Process for the preparation of alkylbenzenes substituted by radicals containing fluorine | BAYER AG (DE) | 1983-07-27 | — | — | EP | disclosed |
| EP-0063873-A1 | Haloalkoxy-substituted diphenyl ethers; their use as herbicides and in herbicidal compositions and processes of making them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180133170-A1 | METHODS AND COMPOSITIONS FOR TREATING DISORDERS | TRPA1, TRPV1, TRPV3 | ALDH1A1 968/4885TSHR 3225/4885LTA4H 258/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.