Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | BCR | P11274 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | BMPR1B | O00238 | 2/20 | 0.38 |
| ▸ | ACVR1B | P36896 | 2/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.38 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.38 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991078 | 0.89 | PDE4A (0.42) | HDAC1HDAC6PDE4APDE4BPDE4C | |
| SCHEMBL8991397 | 0.89 | PDE4A (0.51) | HDAC1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8991091 | 0.87 | EGFR (0.43) | HDAC1HDAC6ABL1NPC1RAB9A | |
| SCHEMBL8991152 | 0.86 | PDE4A (0.40) | HDAC1HDAC6PDE4APDE4BPDE4C | |
| SCHEMBL8991138 | 0.81 | ABL1 (0.43) | HDAC1HDAC6ABL1BCRPDE4A | |
| SCHEMBL8991066 | 0.80 | ALDH1A1 (0.44) | HDAC1HDAC6NPC1RAB9AHPGD | |
| SCHEMBL8991237 | 0.79 | PDE4A (0.42) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL8990936 | 0.78 | ADK (0.33) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL8991346 | 0.78 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DNPC1 | |
| SCHEMBL8991031 | 0.75 | KDM4E (0.41) | ABL1HPGDALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |