Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990972 | 0.90 | MEN1 (0.46) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL8991108 | 0.89 | KDM4E (0.46) | AURKARPS6KB1MMP13KDM4ETSHR | |
| SCHEMBL8991147 | 0.89 | GAA (0.39) | RPS6KB1MEN1NPC1RAB9AKMT2A | |
| SCHEMBL8991137 | 0.84 | AURKA (0.40) | AURKARPS6KB1MEN1NPC1RAB9A | |
| SCHEMBL8991129 | 0.83 | PDE4A (0.41) | AURKARPS6KB1MEN1NPC1RAB9A | |
| SCHEMBL8991328 | 0.82 | ALDH1A1 (0.44) | AURKARPS6KB1MEN1NPC1RAB9A | |
| SCHEMBL8991097 | 0.82 | CCR9 (0.37) | MEN1NPC1RAB9AKMT2AKDM4E | |
| SCHEMBL8991130 | 0.82 | MEN1 (0.39) | AURKARPS6KB1MEN1NPC1RAB9A | |
| SCHEMBL8991221 | 0.82 | MEN1 (0.39) | AURKARPS6KB1MEN1NPC1RAB9A | |
| SCHEMBL8991207 | 0.81 | AURKA (0.40) | AURKARPS6KB1NPC1RAB9AMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |