Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 5/20 | 0.44 |
| ▸ | ABL1 | P00519 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.37 |
| ▸ | PRKDC | P78527 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991099 | 0.89 | KDM4E (0.48) | KDM4EHTTHSD17B10TSHRMAPK1 | |
| SCHEMBL8991130 | 0.88 | MEN1 (0.39) | KDM4EHTTHSD17B10TSHRMAPK1 | |
| SCHEMBL8991251 | 0.86 | KDM4E (0.49) | KDM4EHTTHSD17B10TSHRMAPK1 | |
| SCHEMBL8991048 | 0.86 | KDM4E (0.57) | KDM4EHTTHSD17B10TSHRMAPK1 | |
| SCHEMBL8991162 | 0.81 | KDM4E (0.46) | KDM4EHTTHSD17B10TSHRMAPK1 | |
| SCHEMBL8991108 | 0.81 | KDM4E (0.46) | KDM4EHTTHSD17B10TSHRMAPK1 | |
| SCHEMBL8991123 | 0.80 | KDM4E (0.44) | KDM4EHTTHSD17B10TSHRMAPK1 | |
| SCHEMBL8991072 | 0.79 | LRRK2 (0.51) | KDM4EHTTHSD17B10TSHRMAPK1 | |
| SCHEMBL8991267 | 0.79 | KDM4E (0.48) | KDM4EHTTHSD17B10TSHRMAPK1 | |
| SCHEMBL8991101 | 0.78 | RIPK2 (0.42) | KDM4EHTTHSD17B10TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |