Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | GLA | P06280 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | CASP1 | P29466 | 3/20 | 0.48 |
| ▸ | CASP7 | P55210 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 5/20 | 0.41 |
| ▸ | SRC | P12931 | 3/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991011 | 0.90 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL8991047 | 0.88 | ALDH1A1 (0.46) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL8991251 | 0.87 | KDM4E (0.49) | KDM4EALDH1A1HSD17B10GAAHPGD | |
| SCHEMBL8991371 | 0.85 | MAPK1 (0.44) | KDM4EHSD17B10MAPK1TSHRHTT | |
| SCHEMBL8991048 | 0.84 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL8991022 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL8991284 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL8991144 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1HSD17B10GAANPSR1 | |
| SCHEMBL8991293 | 0.78 | GLA (0.58) | KDM4EALDH1A1HSD17B10GLAGAA | |
| SCHEMBL8991320 | 0.78 | ALDH1A1 (0.47) | KDM4EALDH1A1HSD17B10GLAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |