Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886269 | 0.80 | MAPT (0.48) | GAAMAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL5696647 | 0.74 | RAB9A (0.57) | GAAMAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL2858346 | 0.69 | PKM (0.63) | GAASMN1; SMN2HTTLMNAALOX15 | |
| SCHEMBL10903296 | 0.69 | KMT2A (0.67) | GAAHTTLMNAALOX15KMT2A | |
| SCHEMBL13928559 | 0.69 | KMT2A (0.51) | GAASMN1; SMN2ALOX15TP53KMT2A | |
| SCHEMBL11455819 | 0.69 | MAPT (0.53) | GAAMAPTSMN1; SMN2HTTLMNA | |
| SCHEMBL7521913 | 0.68 | KMT2A (0.57) | GAASMN1; SMN2HTTLMNAALOX15 | |
| Hydrochloric Acid SCHEMBL10955756 | 0.68 | PKM (0.61) | GAASMN1; SMN2HTTLMNAALOX15 | |
| SCHEMBL8991239 | 0.68 | POLB (0.49) | SMN1; SMN2LMNAMAPK1TP53KMT2A | |
| SCHEMBL19134233 | 0.67 | LMNA (0.72) | SMN1; SMN2HTTLMNAMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419215-B1 | Process for preparing 4-substituted azetidinones | LILLY CO ELI (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5106475-A | Alkylating, deprotecting, electrolytic reduction; intermediate for beta-lactam antibiotics | ELI LILLY AND COMPANY (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0419215-A2 | Process for preparing 4-substituted azetidinones | ELI LILLY AND COMPANY (US) | 1991-03-27 | — | — | EP | disclosed |