Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.37 |
| ▸ | CCR9 | P51686 | 4/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991169 | 0.89 | MAPK1 (0.45) | MAPK1KDM4ETSHRHTTHSD17B10 | |
| SCHEMBL8991251 | 0.88 | KDM4E (0.49) | MAPK1KDM4ETSHRHTTHSD17B10 | |
| SCHEMBL8991400 | 0.88 | MEN1 (0.36) | MAPK1KDM4ETSHRHTTHSD17B10 | |
| SCHEMBL8991048 | 0.85 | KDM4E (0.57) | MAPK1KDM4ETSHRHTTHSD17B10 | |
| SCHEMBL8991267 | 0.85 | KDM4E (0.48) | MAPK1KDM4ETSHRHTTHSD17B10 | |
| SCHEMBL8991379 | 0.80 | KDM4E (0.44) | MAPK1KDM4ETSHRHTTHSD17B10 | |
| SCHEMBL8991185 | 0.80 | KDM4E (0.41) | MAPK1KDM4ETSHRHTTHSD17B10 | |
| SCHEMBL8991144 | 0.80 | KDM4E (0.48) | MAPK1KDM4ETSHRHTTHSD17B10 | |
| SCHEMBL8991189 | 0.79 | LRRK2 (0.52) | MAPK1KDM4ETSHRHTTHSD17B10 | |
| SCHEMBL8991269 | 0.78 | PI4KA (0.39) | MAPK1KDM4ETSHRHTTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |