Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991072 | 0.88 | LRRK2 (0.51) | MEN1KMT2ALRRK2KDM4EHSD17B10 | |
| SCHEMBL8991158 | 0.88 | KMT2A (0.49) | MEN1KMT2ANPC1RAB9ALRRK2 | |
| SCHEMBL8990982 | 0.87 | GAA (0.42) | MEN1KMT2ANPC1RAB9ALRRK2 | |
| SCHEMBL8991348 | 0.81 | ALDH1A1 (0.44) | MEN1KMT2ANPC1RAB9ALRRK2 | |
| SCHEMBL8991221 | 0.80 | MEN1 (0.39) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL8991130 | 0.80 | MEN1 (0.39) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL8991316 | 0.80 | ALDH1A1 (0.55) | MEN1KMT2ALRRK2KDM4EHSD17B10 | |
| SCHEMBL8991067 | 0.80 | KDM4E (0.39) | MEN1KMT2ANPC1RAB9ALRRK2 | |
| SCHEMBL8991238 | 0.78 | AURKA (0.40) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL8991137 | 0.78 | AURKA (0.40) | MEN1KMT2ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |