Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | GLA | P06280 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991189 | 0.88 | LRRK2 (0.52) | KDM4EGLAKMT2AALDH1A1GAA | |
| SCHEMBL8990982 | 0.88 | GAA (0.42) | KDM4EGLAKMT2AALDH1A1GAA | |
| SCHEMBL8991158 | 0.86 | KMT2A (0.49) | KDM4EGLAKMT2AALDH1A1GAA | |
| SCHEMBL8991316 | 0.85 | ALDH1A1 (0.55) | KDM4EGLAKMT2AALDH1A1GAA | |
| SCHEMBL8991094 | 0.81 | MEN1 (0.37) | KDM4EGLAKMT2AALDH1A1GAA | |
| SCHEMBL8991400 | 0.80 | MEN1 (0.36) | KDM4EGLAKMT2AALDH1A1GAA | |
| SCHEMBL8991276 | 0.80 | MEN1 (0.40) | KDM4EGLAKMT2AALDH1A1GAA | |
| SCHEMBL8991097 | 0.77 | CCR9 (0.37) | KDM4EKMT2ALMNAMEN1NPC1 | |
| SCHEMBL8991348 | 0.77 | ALDH1A1 (0.44) | KDM4EGLAKMT2AALDH1A1GAA | |
| SCHEMBL7701007 | 0.77 | DYRK1A (0.54) | KDM4EKMT2ALRRK2MEN1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |