Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10903296 | 0.73 | KMT2A (0.67) | ALDH1A1NPC1RAB9AHTTKMT2A | |
| SCHEMBL6186553 | 0.71 | KMT2A (0.56) | ALDH1A1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL3623600 | 0.70 | KMT2A (0.62) | ALDH1A1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL5696647 | 0.69 | RAB9A (0.57) | ALDH1A1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL10964144 | 0.67 | KMT2A (0.57) | ALDH1A1NPC1RAB9AHTTKMT2A | |
| SCHEMBL9344656 | 0.67 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL10414788 | 0.67 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL3498895 | 0.66 | LMNA (0.78) | ALDH1A1SMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL31503975 | 0.66 | LMNA (0.78) | ALDH1A1NPC1RAB9AKMT2AGAA | |
| SCHEMBL23182750 | 0.66 | SMN1; SMN2 (0.55) | SMN1; SMN2RAB9AHTTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0419215-B1 | Process for preparing 4-substituted azetidinones | LILLY CO ELI (US) | 1996-07-24 | — | — | EP | disclosed |
| US-5106475-A | Alkylating, deprotecting, electrolytic reduction; intermediate for beta-lactam antibiotics | ELI LILLY AND COMPANY (US) | 1992-04-21 | — | — | US | disclosed |
| EP-0419215-A2 | Process for preparing 4-substituted azetidinones | ELI LILLY AND COMPANY (US) | 1991-03-27 | — | — | EP | disclosed |