Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCR9 | P51686 | 5/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PI4KA | P42356 | 1/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8991094 | 0.90 | MEN1 (0.37) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL8991286 | 0.89 | GAA (0.41) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL8991371 | 0.88 | MAPK1 (0.44) | MEN1KMT2AKDM4EHSD17B10TSHR | |
| SCHEMBL8991047 | 0.86 | ALDH1A1 (0.46) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL8991097 | 0.81 | CCR9 (0.37) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL8991130 | 0.81 | MEN1 (0.39) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL8991067 | 0.80 | KDM4E (0.39) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL8991141 | 0.80 | PDE4A (0.38) | MEN1KMT2ANPC1RAB9APDE4A | |
| SCHEMBL8990963 | 0.79 | MEN1 (0.48) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL8991134 | 0.79 | GAA (0.42) | MEN1KMT2ANPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |