SCHEMBL8991935

SCHEMBL8991935

CC1(C)C(=O)NC(=S)NC1=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.39
KMT2A Q03164 4/20 0.38
MAPT P10636 4/20 0.38
MEN1 O00255 3/20 0.38
PDK2 Q15119 2/20 0.36
PDK4 Q16654 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
POLB P06746 1/20 0.34
GAA P10253 1/20 0.34
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 2/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
HTT P42858 1/20 0.31
TP53 P04637 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylbarbiturate SCHEMBL296700 0.73 LMNA (0.48) LMNAKMT2AMAPTMEN1PDK2
Dimethylbarbiturate SCHEMBL31271990 0.71 LMNA (0.46) LMNAKMT2AMAPTMEN1PDK2
SCHEMBL3294095 0.71
SCHEMBL321827 0.69 LMNA (0.64) LMNAKMT2AMAPTMEN1SMN1; SMN2
SCHEMBL1119074 0.67 LMNA (0.61) LMNAKMT2AMAPTMEN1SMN1; SMN2
SCHEMBL14265308 0.67 LMNA (0.31) LMNA
SCHEMBL12965826 0.67 PDK2 (0.50) KMT2AMAPTMEN1PDK2PDK4
SCHEMBL5483954 0.65
SCHEMBL10595759 0.64 LMNA (0.36) LMNA
SCHEMBL9591821 0.63 PDK2 (0.71) LMNAKMT2AMAPTMEN1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960362-B2 Compound and organic photoelectric device, image sensor and electronic device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2018-05-01 US disclosed
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME Samsung Electronics Co .. Ltd. (KR) 2017-11-30 US disclosed
US-7410745-B2 Photothermographic material and image forming method using same FUJIFILM CORPORATION (JP) 2008-08-12 US disclosed
US-7410745-B2 Photothermographic material and image forming method using same FUJIFILM CORPORATION (JP) 2008-08-12 US disclosed
EP-1431813-B1 Photothermographic material with high iodide content and image forming method using same FUJI PHOTO FILM CO LTD (JP) 2007-02-14 EP disclosed
EP-0719304-A1 PROCESS FOR THE PRODUCTION OF CYANINE DYES AGFA-GEVAERT N.V. (BE) 1996-07-03 EP disclosed
WO-1995007950-A1 PROCESS FOR THE PRODUCTION OF CYANINE DYES AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) 1995-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170346016-A1 COMPOUND AND ORGANIC PHOTOELECTRIC DEVICE, IMAGE SENSOR AND ELECTRONIC DEVICE INCLUDING THE SAME PPOX, PIEZO1, CYP1A1 LMNA 4498/4885KMT2A 1370/4885MAPT 2370/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.