Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 3/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955338 | 0.79 | SLC1A1 (0.56) | SLC1A1SLC1A3SLC1A2KMT2ACYP1A2 | |
| SCHEMBL10472894 | 0.79 | SLC1A1 (0.56) | SLC1A1SLC1A3SLC1A2KMT2ACYP1A2 | |
| SCHEMBL7603543 | 0.77 | SLC1A1 (0.47) | SLC1A1SLC1A3SLC1A2KMT2ACYP1A2 | |
| SCHEMBL4409725 | 0.73 | CA1 (0.41) | KMT2ACYP1A2CYP2C19ALDH1A1CA1 | |
| SCHEMBL4411606 | 0.73 | CA1 (0.41) | KMT2ACYP1A2CYP2C19ALDH1A1CA1 | |
| SCHEMBL620071 | 0.72 | CA1 (0.53) | CYP1A2CYP2C19ALDH1A1CA1CA2 | |
| SCHEMBL4412607 | 0.70 | CA1 (0.43) | KMT2ACYP1A2CYP2C19ALDH1A1CA1 | |
| SCHEMBL9736749 | 0.69 | CA1 (0.35) | SLC1A1SLC1A3SLC1A2KMT2ACYP1A2 | |
| SCHEMBL9735971 | 0.69 | CA1 (0.35) | SLC1A1SLC1A3SLC1A2KMT2ACYP1A2 | |
| Bicarbonate SCHEMBL9066694 | 0.68 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504078-A | α-glucosidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1996-04-02 | — | — | US | disclosed |
| EP-0532668-B1 | NOVEL ALPHA-GLUCOSIDASE INHIBITORS | MERRELL DOW PHARMA (US) | 1995-11-15 | — | — | EP | disclosed |
| EP-0345104-B1 | Novel Alpha-glucosidase inhibitors | MERRELL DOW PHARMA (US) | 1995-11-02 | — | — | EP | disclosed |
| EP-0532668-A1 | NOVEL -g(a)-GLUCOSIDASE INHIBITORS. | MERRELL DOW PHARMA (US) | 1993-03-24 | — | — | EP | disclosed |
| US-5157116-A | Antidiabetic agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-10-20 | — | — | US | disclosed |
| WO-1991018915-A1 | NOVEL α-GLUCOSIDASE INHIBITORS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-12-12 | — | — | WO | disclosed |
| EP-0345104-A2 | Novel Alpha-glucosidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-12-06 | — | — | EP | disclosed |
| EP-0344383-A1 | Novel alpha-Glucosidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-12-06 | — | — | EP | disclosed |