Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663366 | 0.94 | SCN8A (0.47) | SCN8ACYP3A4CYP2D6CYP2C9HRH1 | |
| SCHEMBL8992092 | 0.79 | SCN8A (0.39) | SCN8A | |
| SCHEMBL8824506 | 0.77 | SCN8A (0.37) | SCN8ACYP3A4CYP2D6CYP2C9PTGS1 | |
| SCHEMBL8824433 | 0.74 | SCN8A (0.38) | SCN8ACYP3A4CYP2D6CYP2C9PTGS1 | |
| SCHEMBL8824480 | 0.74 | SCN8A (0.38) | SCN8ACYP3A4CYP2D6CYP2C9PTGS1 | |
| SCHEMBL8922786 | 0.73 | SCN8A (0.42) | SCN8ACYP3A4CYP2D6CYP2C9HRH1 | |
| SCHEMBL8923732 | 0.72 | SCN8A (0.43) | SCN8ACYP3A4CYP2D6CYP2C9HRH1 | |
| SCHEMBL8824523 | 0.72 | SCN8A (0.37) | SCN8AMAPTSMN1; SMN2 | |
| SCHEMBL8923501 | 0.72 | SCN8A (0.49) | SCN8ACYP3A4CYP2D6CYP2C9HRH1 | |
| SCHEMBL8554117 | 0.70 | GRM5 (0.39) | SCN8ALMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763461-A | ANTIPICORNAVIRAL AGENTS | SANOFI (FR) | 1998-06-09 | — | — | US | disclosed |