Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.40 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922786 | 0.84 | SCN8A (0.42) | SCN8ACYP3A4CYP2D6CYP2C9CYP19A1 | |
| SCHEMBL7301110 | 0.80 | CYP3A4 (0.59) | TDP1L3MBTL1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8992092 | 0.77 | SCN8A (0.39) | SCN8AVNN1 | |
| SCHEMBL8663366 | 0.76 | SCN8A (0.47) | SCN8ACYP3A4CYP2D6CYP2C9HRH1 | |
| SCHEMBL8924199 | 0.76 | SCN8A (0.46) | SCN8ATDP1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL8921466 | 0.74 | NR1I2 (0.45) | SCN8ATDP1L3MBTL1CYP3A4CYP2D6 | |
| SCHEMBL10474110 | 0.73 | TDP1 (0.48) | TDP1L3MBTL1CYP2A6HRH1PTAFR | |
| SCHEMBL9090767 | 0.73 | SCN8A (0.35) | SCN8A | |
| SCHEMBL8824523 | 0.72 | SCN8A (0.37) | SCN8A | |
| SCHEMBL8665185 | 0.72 | SCN8A (0.43) | SCN8ACYP3A4CYP2D6CYP2C9HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |