Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | UTRN | P46939 | 2/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992331 | 0.86 | PPARG (0.39) | NPY5RALDH1A1 | |
| SCHEMBL8992228 | 0.81 | ALDH1A1 (0.42) | HDAC1EPHX2HSD17B1NPY5RDGAT1 | |
| SCHEMBL8992208 | 0.76 | ALDH1A1 (0.53) | HDAC1EPHX2NPY5RALDH1A1RECQL | |
| SCHEMBL8992210 | 0.76 | ALDH1A1 (0.43) | HDAC1EPHX2NPY5RALDH1A1RECQL | |
| SCHEMBL8925129 | 0.73 | UTRN (0.39) | NPY5RALDH1A1AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL8992236 | 0.72 | TACR1 (0.42) | HDAC1EPHX2HSD17B1NPY5R | |
| SCHEMBL8925123 | 0.72 | UTRN (0.39) | HDAC1NPY5RUTRN | |
| SCHEMBL8925520 | 0.67 | ALDH1A1 (0.40) | NPY5RALDH1A1RECQL | |
| SCHEMBL10331192 | 0.66 | CYP1A2 (0.52) | EPHX2NPY5RNPC1POLBCASP3 | |
| SCHEMBL9704697 | 0.64 | ALDH1A1 (0.50) | HDAC1NPY5RALDH1A1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489717-A | Glutamate (NMDA) receptor antagonists | WARNER-LAMBERT COMPANY | 1996-02-06 | — | — | US | claimed |