Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 7/20 | 0.58 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.51 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PTPRF | P10586 | 2/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562520 | 0.89 | NTRK1 (0.51) | PTPRCNTRK1KDM4EALDH1A1GLA | |
| SCHEMBL9562391 | 0.80 | NTRK1 (0.54) | NTRK1KDM4EALDH1A1GLAGAA | |
| SCHEMBL7719612 | 0.78 | S100A4 (0.44) | PTPRCNTRK1NSD2KDM4EALDH1A1 | |
| SCHEMBL29094065 | 0.77 | CCR6 (0.51) | NTRK1HKDC1KDM4EALDH1A1GLA | |
| SCHEMBL6237555 | 0.74 | PTPRC (1.00) | PTPRCPTPN1PTPRFCDC25B | |
| SCHEMBL18392178 | 0.73 | KDM4E (0.61) | NTRK1KDM4EALDH1A1GLAGAA | |
| SCHEMBL8992318 | 0.71 | PTPRC (0.70) | PTPRCNSD2OPRM1OPRD1HKDC1 | |
| SCHEMBL8992603 | 0.71 | PTPRC (0.50) | PTPRCNTRK1NSD2OPRM1OPRD1 | |
| SCHEMBL17698003 | 0.70 | NTRK1 (0.66) | NTRK1CYP2C19HSD17B10 | |
| SCHEMBL27353563 | 0.70 | NTRK1 (0.76) | NTRK1KDM4EALDH1A1CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560682-B1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | OREAL (FR) | 1996-08-07 | — | — | EP | claimed |
| EP-0560682-A1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560682-B1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | OREAL (FR) | 1996-08-07 | — | — | EP | disclosed |
| EP-0560682-A1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |