Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.50 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | NSD2 | O96028 | 4/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 4/20 | 0.45 |
| ▸ | APAF1 | O14727 | 2/20 | 0.45 |
| ▸ | TDP2 | O95551 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GALK1 | P51570 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8992914 | 0.72 | PTPN1 (0.57) | PTPRCDNMT1NSD2HKDC1APAF1 | |
| SCHEMBL8992258 | 0.71 | PTPRC (0.58) | PTPRCNSD2HKDC1KDM4ENQO2 | |
| SCHEMBL1881442 | 0.68 | NR4A2 (0.51) | MEN1KMT2ABLMATMKDM4E | |
| SCHEMBL6237555 | 0.67 | PTPRC (1.00) | PTPRCPTPN1CDC25B | |
| SCHEMBL8170195 | 0.66 | ATP4A (0.48) | MEN1KMT2AKDM4ENQO2MAPT | |
| SCHEMBL20043018 | 0.66 | CDC25B (0.44) | PTPRCDNMT1NSD2HKDC1APAF1 | |
| SCHEMBL20933741 | 0.66 | CA12 (0.39) | KDM4ENQO2ALDH1A1GAACYP2C9 | |
| SCHEMBL20110558 | 0.66 | KDM4E (0.40) | MEN1KMT2AKDM4ENQO2MAPT | |
| SCHEMBL65389 | 0.65 | KDM4E (0.46) | MEN1KMT2AKDM4ENQO2 | |
| SCHEMBL27522434 | 0.65 | KDM4E (0.47) | BLMKDM4ENQO2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560682-B1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | OREAL (FR) | 1996-08-07 | — | — | EP | claimed |
| EP-0560682-A1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560682-B1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | OREAL (FR) | 1996-08-07 | — | — | EP | disclosed |
| EP-0560682-A1 | Keratinous fibres dye compositions with 4-monoindolyl 1,2-naphthochinones, 4-monoindolyl 1,2-naphthoquinones | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |