Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.48 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.44 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9561880 | 0.84 | PTPRC (0.51) | NTRK1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9572008 | 0.83 | APAF1 (0.45) | NTRK1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3852975 | 0.81 | KDM4E (0.51) | NTRK1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9572015 | 0.81 | RAB9A (0.43) | NTRK1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8992258 | 0.80 | PTPRC (0.58) | NTRK1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9562520 | 0.80 | NTRK1 (0.51) | NTRK1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL18392178 | 0.79 | KDM4E (0.61) | NTRK1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9572029 | 0.77 | NPC1 (0.40) | NTRK1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL17698003 | 0.76 | NTRK1 (0.66) | NTRK1HSD17B10CYP2C19GPR3TDP1 | |
| SCHEMBL27353563 | 0.76 | NTRK1 (0.76) | NTRK1ALDH1A1KDM4EHSD17B10CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560684-A1 | 1,4-naphthoquinone or 1,4-naphthalenediol compounds di- or tri-indolyl substituted, processes for their preparation and their use for dyeing keratinous material | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560684-A1 | 1,4-naphthoquinone or 1,4-naphthalenediol compounds di- or tri-indolyl substituted, processes for their preparation and their use for dyeing keratinous material | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |