Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.57 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.54 |
| ▸ | CCR6 | P51684 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.54 |
| ▸ | RAF1 | P04049 | 1/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9562546 | 0.90 | BACE1 (0.57) | BACE1HKDC1CCR6MAPTMAPK1 | |
| SCHEMBL9561883 | 0.85 | HKDC1 (0.52) | BACE1HKDC1CCR6MAPTMAPK1 | |
| SCHEMBL9562286 | 0.84 | CCR6 (0.62) | BACE1HKDC1CCR6MAPTMAPK1 | |
| SCHEMBL9562267 | 0.79 | PTPRC (0.55) | BACE1HKDC1CCR6PTPRCNSD2 | |
| SCHEMBL8992318 | 0.78 | PTPRC (0.70) | HKDC1CCR6MAPTKDM4EALDH1A1 | |
| SCHEMBL9562302 | 0.77 | PTPRC (0.55) | BACE1HKDC1CCR6PTPRC | |
| SCHEMBL7716546 | 0.76 | CCR6 (0.53) | HKDC1CCR6MAPTSMN1; SMN2KDM4E | |
| SCHEMBL9561882 | 0.75 | PTPRC (0.65) | BACE1HKDC1MAPTKDM4ERECQL | |
| SCHEMBL24389333 | 0.73 | BACE1 (1.00) | BACE1MAPTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL29449204 | 0.71 | AURKA (0.65) | BACE1HKDC1MAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | claimed |
| EP-0560683-A1 | Hair coloring compositions with monoindolyl-1,4-naphthoquinones or their leuko derivatives, new monoindolyl-1,4-naphthoquinones and their leukoderivatives | L'OREAL (FR) | 1993-09-15 | — | — | EP | disclosed |