SCHEMBL8992411

SCHEMBL8992411

CC(C)(COS(C)(=O)=O)NC1C=CC(c2ccccc2)(c2ccccc2)C1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.34
GLA P06280 1/20 0.30
MAPT P10636 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8992408 0.84 ALDH1A1 (0.33) ATM
SCHEMBL8992324 0.81 ATM (0.32) ATM
SCHEMBL8992275 0.77 MAOB (0.32)
Hydrochloric Acid SCHEMBL8992323 0.76 MAOB (0.33)
Hydrochloric Acid SCHEMBL8992342 0.75 LMNA (0.37)
SCHEMBL8992438 0.70 SLC6A2 (0.34) ATMMAPTTDP1KDM4E
Hydrochloric Acid SCHEMBL8992338 0.70 CHRM2 (0.37)
SCHEMBL9586923 0.68 HSD11B1 (0.34) ATM
Hydrochloric Acid SCHEMBL8992580 0.68 HTR2A (0.39) MAPT
SCHEMBL8992333 0.68 SLC6A2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0445749-B1 N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments FUJISAWA PHARMACEUTICAL CO (JP) 1996-07-10 EP disclosed
US-5256824-A Anticholinergic agents FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1993-10-26 US disclosed
EP-0445749-A1 N-Monosubstituted cyclopentenylamines, a process for their preparation and their use as medicaments FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-09-11 EP disclosed