Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | STK17B | O94768 | 1/20 | 0.36 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9043834 | 0.76 | ALDH1A1 (0.40) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL18839125 | 0.76 | NPSR1 (0.42) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL8992436 | 0.72 | NPSR1 (0.43) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL8992439 | 0.72 | ALDH1A1 (0.47) | MEN1KMT2APOLBALDH1A1GFER | |
| SCHEMBL27360596 | 0.72 | HTT (0.41) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL9043069 | 0.70 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1GFERHTT | |
| SCHEMBL585017 | 0.68 | ALDH1A1 (0.43) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL28861530 | 0.67 | CPB2 (0.45) | MEN1KMT2AALDH1A1GFERHTT | |
| SCHEMBL18839126 | 0.67 | DRD2 (0.40) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL28675509 | 0.67 | ALDH1A1 (0.39) | MEN1KMT2APOLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510354-A | HYPOTENSIVE AGENTS | TANABE SEIYAKU CO., LTD. (JP) | 1996-04-23 | — | — | US | disclosed |